Dr. Au is the person-in-charge of the paediatric sleep diagnostic and research laboratory in the Prince of Wales Hospital. His research has centered around sleep-disordered breathing and sleep deprivation in children and adolescents. Particularly, he has been investigating the cardiovascular and neurocognitive complications of obstructive sleep apnea (OSA) and the treatment responses, the natural history of OSA from childhood to adulthood, the familial aggregation and heritability of childhood OSA, the screening and diagnosis of OSA, and the epidemiology of OSA in different paediatric age groups. He is currently pursuing the followings:
Precision medicine for childhood OSA: Subtyping of childhood obstructive sleep apnoea
Identification of predictors of clinical outcomes of childhood OSA
Long-term outcomes after treatment for childhood OSA
Night-to-night variability of OSA severity index
Adverse effects of sleep deprivation and effect of sleep extension in children and adolescents
Besides, he runs a regular training course for respiratory and sleep medicine trainees and research personnel involved in the management of paediatric sleep problems. He has been frequently invited to lecture and provide educational workshops in a variety of sleep conferences both locally and in mainland China.
Cognition and behaviour
Young Investigator Award, World Sleep Congress 2019, Vancouver, 2019
Travel Grants for Young Investigator, 2nd Congress of Asian Society of Sleep Medicine (ASSM), Seoul, 2018
Best Oral Presentation Award, 20th HKSPRA Annual Scientific Meeting cum 9th Cross-Strait Paediatric Respirology Congress, Hong Kong, 2017
Best Oral Presentation Award (1st runner up), Hong Kong Paediatric Society Annual Scientific Meeting, Hong Kong, 2015
Best Oral Presentation Award (2nd prize), Hong Kong Paediatric Society Annual Scientific Meeting, Hong Kong, 2007
*Au CT, *Chan KCC, Lee DLY, Leung N, Chow SMW, Chow JS, et al. Effect of surgical intervention for mild childhood obstructive sleep apnoea on attention and behavioural outcomes: A randomized controlled study. Respirology (in press) doi.org/10.1111/resp.14050. (* Joint first authors)
Lan Q-Y, Chan KC, Yu KN, Chan NY, Wing YK, Li AM, Au CT. Sleep duration in preschool children and impact of screen time. Sleep Med. 2020;76:48-54.
*Au CT, *Chan KC, Zhang J, Liu KH, Chu WCW, Wing YK, Li AM. Intermediate phenotypes of childhood obstructive sleep apnea. J Sleep Res. 2020;e13191. (* Joint first authors)
Chan KC, Au CT, Hui LL, Wing YK, Li AM. Childhood OSA is an independent determinant of blood pressure in adulthood: longitudinal follow-up study. Thorax. 2020;75(5):422-431.
Au CT, Zhang J, Cheung JYF, Chan KCC, Wing YK, Li AM. Familial Aggregation and Heritability of Obstructive Sleep Apnea Using Children Probands. J Clin Sleep Med. 2019;15(11):1561-1570.
Chan KC, Au CT, Hui LL, Ng SK, Wing YK, Li AM. How OSA Evolves From Childhood to Young Adulthood: Natural History From a 10-Year Follow-up Study. Chest 2019;156(1):120-130.
Au CT, Chan KC, Liu KH, Chu WCW, Wing YK, Li AM. Potential anatomical markers of obstructive sleep apnea in prepubertal children. J Clin Sleep Med. 2018;14(12): 1979-1986.
Li JWS, Au CT, Chan KCC, Chook P, Wing YK, Li AM. Short sleep duration is weakly associated with carotid intima-media thickness in adolescents. J Pediatr. 2018;195:80-84.
Au CT, Ho CK, Wing YK, Lam HS, Li AM. Acute and chronic effects of sleep duration on blood pressure. Pediatrics. 2014;133(1):e64-72.
Au CT, Ho CK, Wing YK, Li AM. The effect of childhood obstructive sleep apnea on ambulatory blood pressure is modulated by the distribution of respiratory events during rapid eye movement and nonrapid eye movement sleep. Sleep Med. 2013;14(12): 1317-22.
Au CT, Li AM. Obstructive sleep breathing disorders. Pediatr Clin North Am. 2009;56(1):243-59, xii.
Complete List of Published Work in My Bibliography: