Telephone (office): (852) 3505-2859

E-mail:    agnes.syl@cuhk.edu.hk

Publons: ABD-6851-2020

ORCID:    0000-0001-8249-4478

Dr. LEUNG Sze Yin, Agnes
梁詩彥醫生

  • Assistant Professor, Department of Paediatrics

MBChB, MRCPCH, FHKCPaed, FHKAM(Paed)

Biography

Dr. Agnes Leung is a specialist in Paediatric Immunology, Allergy and Infectious Diseases and runs the Specialist Allergy and Infectious Diseases clinics at the Prince of Wales Hospital, which receives territory-wide referrals. She is currently the Honorary Fellow of the Allergy Immunology Research Group at the Murdoch Children’s Research Institute in Melbourne, Australia. The main goal of her current research is to analyze the patterns, causes, and effects of food allergy in the Asia-pacific region, in hope to provide effective preventive methods and safe treatment plans for patients with food allergic disorders.


Her research work on fish allergy diagnostics was awarded the Best Dissertation Award by the Hong Kong College of Paediatricians and she also received the Faculty Innovation Award from the Faculty of Medicine, CUHK, to conduct research on fish immunotherapy in 2018. She holds a patent on the novel allergens isolated from grass carp.


Dr. Leung is currently the Honorary Secretary of the Hong Kong Society of Paediatric Immunology, Allergy and Infectious Diseases (HKSPIAID) and a Council Member of the Hong Kong Institute of Allergy. She is also the Junior leader of the Asia Pacific Academy of Pediatric Allergy, Respirology and Immunology (APAPARI); member of the Allergy Prevention and Anaphylaxis Committees of the World Allergy Organization (WAO) and a Food Allergy Committee member of the Asia Pacific Association of Allergy Asthma and Clinical Immunology (APAAACI).

Research Interests

  • Allergy & Immunology with special interest in food allergy, anaphylaxis and asthma


Honorary Appointments

  • Honorary Resident Specialist, Department of Paediatrics, Prince of Wales Hospital

  • Honorary Fellow, Allergy Immunology Group, Infection and Immunity, Murdoch Children’s Research Institute, The Royal Children’s Hospital, Melbourne, Australia


Professional Service

  • Honorary Secretary, Hong Kong Society of Paediatric Immunology, Allergy and Infectious Diseases

  • Council Member, Hong Kong Institute of Allergy

  • Junior Committee Leader of the Asia Pacific Academy of Pediatric Allergy, Respirology & Immunology (APAPARI)

  • Steering Committee Member of the APAPARI Anaphylaxis Registry

  • Allergy Prevention Committee Member of the World Allergy Organization

  • Anaphylaxis Committee Member of the World Allergy Organization

  • Food Allergy Committee Member of the Asia Pacific Association of Allergy Asthma and Clinical Immunology (APAAACI)

  • Member of the Hong Kong College of Paediatricians Professional & General Affairs Committee


Awards

  • Best Presentation Award in Poster Presentation, The 9th Asian Congress of Pediatric Infectious Diseases (ACPID) 10-12.11.2018, Fukuoka, Japan

  • Best Dissertation Prize 2018, The Hong Kong College of Paediatricians

  • Faculty Innovation Award 2018, Faculty of Medicine, The Chinese University of Hong Kong, 27.8.2018, Hong Kong

  • Best Presentation Award in Oral Presentation, The 67th Annual Meeting of Japanese Society of Allergology 22-24.7.2018, Tokyo, Japan

  • Young Investigator Award, KAAACI-EAAS-SERIN ASIA Joint Congress in conjunction with APAAACI (Young Investigator Award), 10-12.5.2018, Seoul, Korea

  • Young Investigator Award, The Asia-Pacific Association of Pediatric Allergy, Respirology and Immunology 2017 Congress, 3-5.11.2017, Beijing, China


Patents

  • "Improved accuracy of fish allergy diagnosis using grass carp allergens”, US Non-Provisional Patent Application; PCT International Application No. 16/588,517 filed on 30 Sep 2019 and published as Non-Provisional Patent under publication no. US2020/ A1 on 18 Jun 2020

  • "Novel diagnostic allergen biomarkers for shrimp allergy”, Attorney Docket no. -030400US and registration no. 46,213 for US Provisional Patent Application no. 63/034,893 and filed/executed on 4 Jun 2020

  • "Discovery and registration of “Allergen structure of Ctenopharyngodon idella” in the WHO/IUIS Allergen Nomenclature Database and accepted as a new allergen with the name Cten i1.0101; PubMed accession number GEUQ on 9 Jan 2019

Selected Publications

  1. Leung AS*, Tham EH*, Li J, Pacharn P, Takizawa T, Lee E, Xing Y, Leung TF, Hong SJ, Wong GW. The role of the environment in shaping the trends of childhood asthma - an Asian perspective. Pediatr Allergy Immunol. 2021 Mar 24. doi: 10.1111/pai.13508. Epub ahead of print. PMID:33760296.

  2. Turner PJ, Ansotegui IJ, Campbell DE, Cardona V, Ebisawa M, El-Gamal Y, Fineman S, Geller M, Gonzalez-Estrada A, Greenberger PA, Leung ASY, Levin ME, Muraro A, Sánchez Borges M, Senna G, Tanno LK, Yu-Hor Thong B, Worm M; WAO Anaphylaxis Committee. COVID-19 vaccine-associated anaphylaxis: A statement of the World Allergy Organization Anaphylaxis Committee. World Allergy Organ J. 2021 Feb;14(2):100517. doi: 10.1016/j.waojou.2021.100517. Epub 2021 Feb 3. PMID: 33558825.

  3. Li PH*, Chua GT*, Leung ASY*, Chan YC, Chan KKL, Cheung KH, Chong PCY, Ho PPK, Kwan MYW, Lai JCH, Lam KK, Lam TSK, Leung TF, Li TY, Duque JSR, So JLT, Wan KA, Wong HCY, Wu AYY, Lee TH, Ho MHK, Siu AYC. Hong Kong Anaphylaxis Consortium Consensus Statements on prescription of adrenaline autoinjectors in the acute care setting. Asia Pac Allergy. 2021 Jan 6;11(1):e1. doi: 10.5415/apallergy.2021.11.e1. PMID: 33604271; PMCID: PMC7870372.

  4. Leung ASY*, Leung NYH*, Wai CYY, Xu KJY, Lam MCY, Shum YY, Lee TH, Ho MHK, Sou Da Rosa Duque J, Chua GT, Yau YS, Chan WH, Ho PK, Wong GWK, Leung TF. Characteristics of Chinese fish-allergic patients: Findings from double-blind placebo-controlled food challenges. J Allergy Clin Immunol Pract. 2020 Jun;8(6):2098-2100.e8. doi: 10.1016/j.jaip.2020.02.002. Epub 2020 Feb 28.

  5. Leung NYH*, Leung ASY*, Xu KJY, Wai CYY, Lam MCY, Wong GWK, Leung TF. Molecular and Immunological Characterization of Grass Carp (Ctenopharyngodon Idella) Parvalbumin Cten I 1: A Major Fish Allergen in Hong Kong. Pediatr Allergy Immunol. 2020 Apr 22. doi:10.1111/pai.13259.

  6. Li PH*, Leung ASY*, Li RMY, Leung TF, Lau CS, Wong GWK. Increasing incidence of anaphylaxis in Hong Kong from 2009 to 2019 -- discrepancies of anaphylaxis care between adult and pediatric patients. Clin Transl Allergy 10, 51 (2020). doi.org/10.1186/s13601-020-00355-6.

  7. Leung ASY, Leung NYH, Wai CYY, Leung TF, Wong GWK. Allergen immunotherapy for food allergy from the Asian perspective: key challenges and opportunities. Expert Review of Clinical Immunology, 15:2, 153-164, doi: 10.1080/1744666X.2019.1554432.

  8. Leung ASY*, Tham EH*, Pacharn P, Lee SY, Ebisawa M, Lee BW, Wong GW. Anaphylaxis around the world: comparing comparing East and West. Pediatr Allergy Immunol. 2019; 30: 681– 688. doi.org/10.1111/pai.13098.

  9. Leung ASY, Wong GW, Tang ML. Food allergy in the developing world. J Allergy Clin Immunol. 2018 Jan;141(1):76-78.e1. doi: 10.1016/j.jaci.2017.11.008. Epub 2017 Nov 22.