E-mail:    tfleung@cuhk.edu.hk

Publons: E-7728-2013

ORCID:    0000-0002-6469-1926


Administrative support: Ms Angel Kwong

Telephone (office): (852) 3505-2981

Professor LEUNG Ting Fan
梁廷勳教授

  • Alice Ho Miu Ling Nethersole Charity Foundation Professor of Paediatrics, Department of Paediatrics 

  • Founding Director, Hong Kong Hub of Paediatric Excellence (HK HOPE) 

  • Co-Director, Chinese University of Hong Kong-Baylor College of Medicine Joint Center for Medical Genetics 

  • Co-Director, Chinese University of Hong Kong-University Medical Center Utrecht Joint Research Laboratory of Respiratory Virus and Immunobiology

MBChB(CUHK), MD(CUHK), MRCP(UK), FRCPCH, FHKCPaed, FHKAM(Paediatrics), Specialist in Paediatrics

Biography

Professor Leung graduated from The Chinese University of Hong Kong.  He is a professor in Department of Paediatrics and Founding Director of Hong Kong Hub of Paediatric Excellence (HK HOPE) at the same university. He is an Honorary Professor of Peking Union Medical College Hospital and Visiting Professor of Central South University in the People’s Republic of China.  Professor Leung is a Board Member of Asia Pacific Association of Allergy, Asthma and Clinical Immunology.  Locally, he is Vice President of Hong Kong College of Paediatricians and Hong Kong Institute of Allergy.  His main research interests include natural history, novel diagnostics, genetics and host-microbe interactions of allergic diseases in children.

Research Interests

  • Novel diagnosis and treatment for food allergy

  • Genetics and genomics of childhood allergies

  • Host-microbe interaction as determinant of wheezing illnesses and eczema in children


Honorary Appointments

  • Honorary Consultant Paediatrician, New Territories East Cluster, Kwong Wah Hospital and Hong Kong Children’s Hospital

  • International Fellow, American Academy of Allergy Asthma and Immunology

  • Member, European Academy of Allergy and Clinical Immunology

  • Visiting Professor, Department of Paediatrics, Xiang Ya Hospital, Central South University, Changsha, Hunan

  • Honorary Professor, Peking Union Medical College Hospital, Beijing


Professional Service

  • Vice President, Hong Kong College of Paediatricians

  • Immediate Past President, Hong Kong Society for Paediatric Immunology Allergy and Infectious Diseases

  • Vice President, Hong Kong Institute of Allergy

  • Board Member, Asia Pacific Association of Allergy Asthma and Clinical Immunology

  • Associate Editor, Frontiers in Pediatrics (Pulmonology)

  • Editor, Journal of Formosans Medical Association

  • Editorial Board, Asia Pacific Allergy


Academic Engagement in CUHK

  • Postgraduate supervision of nine post-doctoral fellows; six PhD, seven MPhil and 13 MSc students graduated and four PhD students under supervision

  • Academic mentor of two clinical lecturers and supervisor of one Paediatric subspecialty trainee


Awards

  • Abstract Prize, 38th Congress of European Academy of Allergology and Clinical Immunology. Lisbon, Portugal, Jun 2019

  • Best Free Paper Award, Joint Congress of Asia Pacific Association of Allergy, Asthma and Clinical Immunology and Asia Pacific Association of Pediatric Allergy, Respiratory and Immunology. Bangkok, Thailand, Oct 2018

  • Best Poster Presentation Award, 13th Annual Congress of Asian Society for Pediatric Research. Hong Kong, Oct 2017

  • Enhanced Travel Award, 34th Annual Meeting of the European Society for Paediatric Infectious Diseases. Brighton, United Kingdom, May 2016

  • Outstanding Abstract Award, 2013 Joint Congress of Asia Pacific Association of Pediatric Allergy, Respiratory and Immunology and Allergy, Asthma and Immunology Association of Thailand. Bangkok, Thailand, Oct 2013

  • Abstract Prize, World Allergy and Asthma Congress. Milan, Italy, Jun 2013

  • Best Poster Award, 17th Congress of Asian Pacific Society of Respirology. Hong Kong, Dec 2012

  • Abstract Award, 31st Congress of European Academy of Allergology and Clinical Immunology. Geneva, Switzerland, Jun 2012

  • Young Researcher Award, 5th Asian Congress of Pediatric Infectious Diseases, Taipei, Taiwan, Sep 2010

  • Second Prize of Best Poster Presentation, 2nd Guangdong – Hong Kong – Chongqing – Shanghai Paediatric Exchange Meeting. Shenzhen, People’s Republic of China, Jun 2010

  • First runner-up for Young Investigator Award, International Paediatric Respiratory, Allergy and Immunology Congress. Hong Kong, Jul 2004


Patents

  • “Forecasting developmental language and communication outcomes in healthy children”, for Chinese Patent Application no. 202010692253.5 filed on 17 Jul 2020

  • “Improved accuracy of fish allergy diagnosis using grass carp allergens”, US Non-Provisional Patent Application; PCT International Application No. 16/588,517 filed on 30 Sep 2019 and published as Non-Provisional Patent under publication no. US2020/0191797 A1 on 18 Jun 2020

  • “Novel diagnostic allergen biomarkers for shrimp allergy”, Attorney Docket no. 80015-1183308-030400US and registration no. 46,213 for US Provisional Patent Application no. 63/034,893 and filed/executed on 4 Jun 2020

  • "Discovery and registration of “Allergen structure of Ctenopharyngodon idella” in the WHO/IUIS Allergen Nomenclature Database and accepted as a new allergen with the name Cten i 1.0101; PubMed accession number GEUQ01011817.1 on 9 Jan 2019

  • “CD9 as a therapeutic target for hematologic malignancies”, US Provisional Patent PCT international application no. 15/653,325 filed on 18 Jul 2017

Selected Publications

  1. Wai CY, Leung NY, Leung AS, Shum Y, Leung PS, Chu KH, Kwan YW, Lee QU, Wong JS, Lam IC, Li PF, Xu KJ, Lam CY, Sun JL, Wong GW, Leung TF (corresponding author). Cell-based functional IgE assays are superior to conventional allergy tests for shrimp allergy diagnosis. J Allergy Clin Immunol Pract 2020 Sep 11. doi: 10.1016/j.jaip.2020.08.057.

  2. Leung NY*, Leung AS*, Xu KJ, Wai CY, Lam CY, Wong GW, Leung TF (corresponding author). Molecular and immunological characterization of grass carp (Ctenopharyngodon idella) parvalbumin Cten i 1: a major fish allergen in Hong Kong. Pediatr Allergy Immunol 2020 Apr 22. doi: 10.1111/pai.13259. (* co-first authors)

  3. Leung AS*, Leung NY*, Wai CY, Xu KJ, Lam MC, Shum Y, Lee TH, Ho MH, Rosa Duque JS, Chua GT, Yau YS, Chan WH, Ho PK, Wong GW, Leung TF (corresponding author). Characteristics of Chinese fish-allergic patients: findings from double-blind placebo-controlled food challenges. J Allergy Clin Immunol Pract 2020;8:2098-100. (* co-first authors)

  4. Yau JW*, Hou JP*, Tsui SKW, Leung TF, Cheng NS, Yam JC, Kam KW, Vishal J, Hon KL. Characterization of ocular and nasopharyngeal microbiome in allergic rhinoconjunctivitis. Pediatr Allergy Immunol 2019;30:624-31. (* co-first authors)

  5. Tang MF, Sy HY, Kwok JS, Tam WH, Hon KL, Tung CK, Wong GW, Tsui SKW, Leung TF (corresponding author). Eczema susceptibility and composition of faecal microbiota at 4 weeks of age: a pilot study in Chinese infants. Br J Dermatol 2016;174:898-900.

  6. Leung TF, Ko FW, Sy HY, Tsui SKW, Wong GW. Differences in asthma genetics between Chinese and other populations. J Allergy Clin Immunol 2014;133:42-8.

  7. Leung TF (corresponding author), To MY, Yeung AC, Wong YS, Wong GW, Chan PK. Multiplex molecular detection of respiratory pathogens in children with asthma exacerbation. Chest 2010;137:348-54.

  8. Leung TF (corresponding author), Wong GW, Ko FW, Lam CW, Fok TF. Clinical and atopic parameters and airway inflammatory markers in childhood asthma: a factor analysis. Thorax 2005;60:822-6.

  9. Leung TF (corresponding author), Tang NL, Li CY, Lam CW, Wong GW, Fok TF. Association between TARC C-431T and atopy and asthma in children. J Allergy Clin Immunol 2004;114:199-202.

  10. Leung TF (corresponding author), Wong CK, Chan IH, Ip WK, Lam CW, Wong GW. Plasma concentration of thymus and activation-regulated chemokine is elevated in childhood asthma. J Allergy Clin Immunol 2002;110:404-9.