Professor Wong Wing Kin Gary

Personal Information

Professor Wong Wing Kin Gary

MD, FRCPC, FHKAM, Professor, Department of Paediatrics

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Dr Gary WK Wong, Professor, has been working in the Department of Paediatrics at the Chinese University of Hong Kong for over 20 years. He obtained his undergraduate medical education from the University of Alberta, Canada. He subsequently received fellowship training at University of British Columbia, and Children’s Hospital of British Columbia, Canada. He returned to Hong Kong and joined the Chinese University of Hong Kong in 1990. He subsequently went to the Children’s Hospital at Munich as a research fellow in 2001. Dr Wong has strong interest in different aspects of allergic and autoimmune diseases. In particular, he is interested in the epidemiology and environmental determinants of asthma and related allergic disorders. He is currently an executive member of the Global Initiative for Asthma and he is one of the steering committee members of the ISAAC (International Study of Asthma and Allergies in Childhood) research group. He is also one of the executive members of the Asia-Pacific Association of Pediatric Allergy, Respirology and Immunology (APAPARI). Among other duties within several editorial boards, he is also the Associate Editor for Australasia of Pediatric Pulmonology. Dr Wong also participates actively in the Paediatric and medical communities in Hong Kong. He is the current Council member of the Hong Kong Society of Respirology (HKSPR). He is also the Chairman of the Asthma Focus Group of the HKSPR.



Current appointments

  • Professor, Department of Paediatrics and School of Public Health


Research Interests

  • Epidemiology of Asthma and Allergic disorders

  • Environmental determinants and gene environmental interaction of asthma

  • Non-invasive asthma monitoring and assessment

  • Lung function assessment in young children


Recent Publications

  1. Wong GW. Air pollution and health. Lancet Respir Med 2014;2:8-9.

  2. Wong GW, Miravitlles M, Chisholm A, Krishnan J.  Respiratory guidelines- which real world?  Ann Am Thoracic Soc 2014;S2:85-91.

  3. Wong GW, Brunekreef B, Ellwood P, Anderson HR, Asher MI, Crane J, Lai CK. Cooking fuels and prevalence of asthma: a global analysis of phase three of the International Study of Asthma and Allergies in Childhood.  Lancet Respir Med 2013;1:386-94.

  4. Wong GW, Leung TF, Ko FW.  Changing prevalence of allergic diseases in the Asia-pacific region. Allergy Asthma Immunol Res. 2013;5:251-7.

  5. Leung TF, Ko FW, Wong GW.  Recent advances in asthma biomarker research. Ther Adv Respir Dis 2013;7:297-308.

  6. Leung TF, Chan IH, Liu TC, Lam CW, Wong GW.  Relationship between passive smoking exposure and urinary heavy metals and lung functions in preschool children. Pediatr Pulmonol 2013 Jun 28. [Epub ahead of print]

  7. Leung TF, Chan PK, Wong GW, Fok TF, Ng PC.  Respiratory viruses and atypical bacteria triggering severe asthma exacerbation in children. Hong Kong Med J 2013;19:11-4.

  8. Wong GW, Kwon N, Hong JG, Hsu JY, Gunasekera KD.  Pediatric asthma control in Asia: phase 2 of the Asthma Insights and Reality in Asia-Pacific (AIRIAP 2) survey.  Allergy 2013;68:524-30.

  9. Leung TF, Liu TC, Mak KK, Su X, Sy HY, Li AM, Lau JT, Lum S, Wong GW. Reference standards for forced expiratory indices in Chinese preschool children. Pediatr Pulmonol. 2013 Feb 8. [Epub ahead of print]

  10. Ko FW, Leung TF, Wong GW, Chu JH, Sy HY, Hui DS. Determinants of, and reference equation for, exhaled nitric oxide in the Chinese population.  Eur Respir J 2013;42:767-75.

  11. Brunekreef B, Von Mutius E, Wong GW, Odhiambo JA, Clayton TO; ISAAC Phase Three Study Group.  Early life exposure to farm animals and symptoms of asthma, rhinoconjunctivitis and eczema: an ISAAC Phase Three Study.  Int J Epidemiol. 2012;41:753-61.

  12. Chan IH, Kong AP, Leung TF, Tsui TK, Cheung RC, Osaki R, Ho CS, Wong GW, Wong CK, Lam CW, Chan JC, Chan MH.  Cadmium and lead in Hong Kong school children. Pathology. 2012;44:626-31.

  13. Sy HY, Ko FW, Chu HY, Chan IH, Wong GW, Hui DS, Leung TF.  Asthma and bronchodilator responsiveness are associated with polymorphic markers of ARG1, CRHR2 and chromosome 17q21.  Pharmacogenet Genomics 2012;22:517-24.

  14. Wang SS, Hon KL, Sy HY, Kong AP, Chan IH, Tse LY, Lam CW, Wong GW, Chan JC, Leung TF.  Interactions between genetic variants of FLG and chromosome 11q13 locus determine susceptibility for eczema phenotypes.  J Invest Dermatol 2012;132:1930-2.

  15. Leung TF, Ko FW, Wong GW.  Roles of pollution in the prevalence and exacerbations of allergic diseases in Asia.  J Allergy Clin Immunol 2012;129:42-7.

  16. Lam A, Wong GW, Poon CM, Lee SS.  A GIS-Based Assessment of Environmental Influences on Allergy Development in Children.  Asia Pac J Public Health 2011 Dec 20. [Epub ahead of print]

  17. Ko FW, Hui DS, Leung TF, Chu HY, Wong GW, Tung AH, Ngai JC, Ng SS, Lai CK.  Evaluation of the asthma control test: a reliable determinant of disease stability and a predictor of future exacerbations.  Respirology 2012;17:370-8.

  18. Siu WK, Law CY, Lam CW, Mak CM, Wong GW, Ho AY, Ho KY, Loo KT, Chiu SC, Chow LT, Tong SF, Chan AY.  Novel nonsense CDC73 mutations in Chinese patients with parathyroid tumors.  Fam Cancer 2011;10:695-9.

  19. Kong AP, Choi KC, Wong GW, Ko GT, Ho CS, Chan MH, Ozaki R, Ma RC, Lau JT, Chan JC.  Serum concentrations of insulin-like growth factor-I, insulin-like growth factor binding protein-3 and cardiovascular risk factors in adolescents.  Ann Clin Biochem 2011;48:263-9.

  20. Leung TF, Wong YS, Chan IH, Yung E, Sy HY, Lam CW, Wong GW.  Domestic exposure to aeroallergens in Hong Kong families with asthmatic children.  Pediatr Pulmonol 2011;46:632-9.

  21. Leung TF, Ching KW, Kong AP, Wong GW, Chan JC, Hon KL.  Circulating LL-37 is a biomarker for eczema severity in children.  J Eur Acad Dermatol Venereol 2012;26:518-22.

  22. Mak RK, Tse LY, Lam WY, Wong GW, Chan PK, Leung TF.  Clinical spectrum of human rhinovirus infections in hospitalized Hong Kong children.  Pediatr Infect Dis J 2011;30:749-53.

  23. Kong AP, Choi KC, Wong GW, Ko GT, Ho CS, Chan MH, Ozaki R, Ma RC, Lau JT, Chan JC.  Serum concentrations of insulin-like growth factor-I, insulin-like growth factor binding protein-3 and cardiovascular risk factors in adolescents.  Ann Clin Biochem 2011;48:263-9.

  24. Leung TF, Ching KW, Sy HY, Kong AP, Tse LY, Wang SS, Lam CW, Chan JC, Wong GW, Hon KL.  CHIA confers susceptibility to childhood eczema.  Br J Dermatol 2010;163:1360-2.

  25. Lai CK, Ko FW, Bhome A, De Guia TS, Wong GW, Zainudin BM, Nang AN, Boonsawat W, Cho SH, Gunasekera KD, Hong JG, Hsu JY, Viet NN, Yunus F, Mukhopadhyay A.  Relationship between asthma control status, the Asthma Control Test(TM) and urgent health care utilization in Asia.  Respirology 2011;16:688-97.

  26. Leung TF, Ching KW, Sy HY, Kong AP, Tse LY, Wang SS, Lam CW, Chan JC, Wong GW, Hon KL.  CHIA confers susceptibility to childhood eczema.  Br J Dermatol 2010;163:1360-2.

  27. Sy HY, Chan IH, Hon EK, Kong AP, Tang NL, Li CY, Wong GW, Waye MM, Lam CW, Chan JC, Leung TF.  PHF11 is not a major candidate gene for asthma or eczema in Chinese children.  Pediatr Pulmonol 2010;45:890-7.

  28. Wong GW.  Zero tolerance to asthma death.  Hong Kong Med J. 2010 Apr;16(2):84-5.

  29. Leung TF, Wong YS, Chan IH, Yung E, Wong CK, Lam CW, Wong GW.  Indoor determinants of endotoxin and dust mite exposures in Hong Kong homes with asthmatic children.  Int Arch Allergy Immunol. 2010;152(3):279-87.

  30. Mong JL, Ng MC, Guldan GS, Tam CH, Lee HM, Ma RC, So WY, Wong GW, Kong AP, Chan JC, Waye MM.  Associations of the growth hormone receptor (GHR) gene polymorphisms with adiposity and IGF-I activity in adolescents.  Clin Endocrinol 2010;73:313-22.

  31. Genuneit J, Cantelmo JL, Weinmayr G, Wong GW, Cooper PJ, Riikjärv MA, Gotua M, Kabesch M, von Mutius E, Forastiere F, Crane J, Nystad W, El-Sharif N, Batlles-Garrido J, García-Marcos L, García-Hernández G, Morales-Suarez-Varela M, Nilsson L, Bråbäck L, Saraçlar Y, Weiland SK, Cookson WO, Strachan D, Moffatt MF A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2.  Clin Exp Allergy 2009;39:1875-88.

  32. Chan IH, Tang NL, Leung TF, Lam YY, Wong GW, Wong CK, Lam CW.Association of plasma soluble CTLA-4 with lung function and gene polymorphism in Chinese asthmatic children.  Int Arch Allergy Immunol 2010;152:113-21.

  33. Gappa M, Ferkol T, Kovesi T, Landau L, McColley S, Sanchez I, Tal A, Wong GW, Zar H.  Pediatric respiratory medicine--an international perspective.  Pediatr Pulmonol 2010;45:14-24.

  34. Chan MH, Chan IH, Kong AP, Osaki R, Cheung RC, Ho CS, Wong GW, Tong PC, Chan JC, Lam CW. Cold-vapour atomic absorption spectrometry underestimates total mercury in blood and urine compared to inductively-coupled plasma mass spectrometry: an important factor for determining mercury reference intervals. Pathology 2009;41:467-72.

  35. Wong GW, Mahesh PA, Ogorodova L, Leung TF, Fedorova O, Holla AD, Fernandez-Rivas M, Clare Mills EN, Kummeling I, van Ree R, Yazdanbakhsh M, Burney P.  The EuroPrevall-INCO surveys on the prevalence of food allergies in children from China, India and Russia: the study methodology.  Allergy 2010;65:385-90.

  36. Mong JL, Ng MC, Guldan GS, Tam CH, Lee HM, Ma RC, So WY, Wong GW, Kong AP, Chan JC, Waye MM.  Associations of insulin-like growth factor binding protein-3 gene polymorphisms with IGF-I activity and lipid parameters in adolescents.  Int J Obes. 2009;33:1446-53.

  37. Leung TF, Li CY, Lam WY, Wong GW, Cheuk E, Ip M, Ng PC, Chan PK. Epidemiology and clinical presentations of human coronavirus NL63 infections in Hong Kong children.  J Clin Microbiol. 2009;47:3486-92.

  38. Leung TF, To MY, Yeung AC, Wong YS, Wong GW, Chan PK.  Multiplex molecular detection of respiratory pathogens in children with asthma exacerbation. Chest 2010;137(2):348-54.

  39. Ma Y, Zhao J, Han ZR, Chen Y, Leung TF, Wong GW.  Very low prevalence of asthma and allergies in schoolchildren from rural Beijing, China.  Pediatr Pulmonol. 2009;44(8):793-9.

  40. Flohr C, Weinmayr G, Weiland SK, Addo-Yobo E, Annesi-Maesano I, Björkstén B, Bråbäck L, Büchele G, Chico M, Cooper P, Clausen M, El Sharif N, Martinez Gimeno A, Mathur RS, von Mutius E, Morales Suarez-Varela M, Pearce N, Svabe V, Wong GW, Yu M, Zhong NS, Williams HC.  How well do questionnaires perform compared with physical examination in detecting flexural eczema? Findings from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Two.  Br J Dermatol 2009;161:846-53.

  41. Ko FW, Leung TF, Wong GW, Ngai J, To KW, Ng S, Hui DS.  Measurement of tumor necrosis factor-alpha, leukotriene B4, and interleukin 8 in the exhaled breath condensate in patients with acute exacerbations of chronic obstructive pulmonary disease.  Int J Chron Obstruct Pulmon Dis 2009;4:79-86.

  42. Ko FW, Leung TF, Hui DS, Chu HY, Wong GW, Wong E, Tung AH, Lai CK. Asthma Control Test correlates well with the treatment decisions made by asthma specialists.  Respirology 2009;14(4):559-66.

  43. Leung TF, Ko FW, Wong GW, Li CY, Yung E, Hui DS, Lai CK.  Predicting changes in clinical status of young asthmatics: clinical scores or objective parameters?  Pediatr Pulmonol. 2009;44:442-9.

  44. Fok AO, Wong GW.  What have we learnt from ISAAC phase III in the Asia-Pacific rim?  Curr Opin Allergy Clin Immunol. 2009;9:116-22.

  45. Leung TF, Ko FW, Sy HY, Wong E, Li CY, Yung E, Hui DS, Wong GW, Lai CK Identifying uncontrolled asthma in young children: clinical scores or objective variables?  J Asthma. 2009;46:130-5.

  46. Leung TF, Yung E, Wong YS, Li CY, Wong GW.  Quality-of-life assessment in Chinese families with food-allergic children.  Clin Exp Allergy 2009;39:890-6.

  47. Leung TF, Li CY, Kong AP, Chan IH, Ng MC, Chan MH, So WY, Wong GW, Lam CW, Chan JC.  PTGDR is not a major candidate gene for asthma and atopy in Chinese children.  Pediatr Allergy Immunol. 2009;20:556-62.

  48. Leung TF, Sy HY, Ng MC, Chan IH, Wong GW, Tang NL, Waye MM, Lam CW. Asthma and atopy are associated with chromosome 17q21 markers in Chinese children.  Allergy 2009;64:621-8.

  49. Leung TF, Kong AP, Chan IH, Choi KC, Ho CS, Chan MH, So WY, Lam CW, Wong GW, Chan JC.  Association between obesity and atopy in Chinese schoolchildren.  Int Arch Allergy Immunol 2009;149(2):133-40.

  50. Wang HY, Wong GW, Chen YZ, Ferguson AC, Greene JM, Ma Y, Zhong NS, Lai CK, Sears MR.  Prevalence of asthma among Chinese adolescents living in Canada and in China.  Canadian Medical Association Journal 2008;179:1133-42.

  51. Kong AP, Ko GT, Ozaki R, Wong GW, Tong PC, Chan JC.  Metabolic syndrome by the new IDF criteria in Hong Kong Chinese adolescents and its prediction by using body mass index.  Acta Paediatr. 2008;97:1738-42.

  52. Leung TF, Yung E, Wong YS, Lam CW, Wong GW.  Parent-reported adverse food reactions in Hong Kong Chinese pre-schoolers: epidemiology, clinical spectrum and risk factors.  Pediatr Allergy Immunol. 2009;20:339-46.

  53. Leung TF, Wong GW.  The Asian side of asthma and allergy.  Curr Opin Allergy Clin Immunol. 2008 Oct;8(5):384-90.

  54. Ellwood P, Williams H, Aït-Khaled N, Björkstén B, Robertson C, Wong GW (ISAAC Phase III Study Group).  Translation of questions: the International Study of Asthma and Allergies in Childhood (ISAAC) experience.  Int J Tuberc Lung Dis. 2009 Sep;13(9):1174-82.

  55. Chan IH, Tang NL, Leung TF, Huang W, Lam YY, Li CY, Wong CK, Wong GW, Lam CW.  Study of gene-gene interactions for endophenotypic quantitative traits in Chinese asthmatic children.  Allergy 2008;63:1031-9.

  56. Chan IH, Tang NL, Leung TF, Huang W, Lam YY, Wong GW, Chan JC, Chan MH, Wong CK, Zhang YP, Lam CW.  Association of early growth response-1 gene polymorphisms with total IgE and atopy in asthmatic children. Pediatr Allergy Immunol 2009;20:142-50.

  57. Kong AP, Choi KC, Ko GT, Wong GW, Ozaki R, So WY, Tong PC, Chan JC. Associations of overweight with insulin resistance, beta-cell function and inflammatory markers in Chinese adolescents.  Pediatr Diabetes 2008;9:488-95.

  58. Kong AP, Choi KC, Cockram CS, Ho CS, Chan MH, Ozaki R, Wong GW, Ko GT, So WY, Tong PC, Lam CW, Lau JT, Chow FC, Chan JC.  Independent associations of alanine aminotransferase (ALT) levels with cardiovascular risk factor clustering in Chinese adolescents.  J Hepatol. 2008;49:115-22.

  59. Ko GT, Ozaki R, Wong GW, Kong AP, So WY, Tong PC, Chan MH, Ho CS, Lam CW, Chan JC.  The problem of obesity among adolescents in Hong Kong: a comparison using various diagnostic criteria.  BMC Pediatr 2008;8:10.

  60. Chong KK, Chiang SW, Wong GW, Tam PO, Ng TK, Hu YJ, Yam GH, Lam DS, Pang CP.  Association of CTLA-4 and IL-13 gene polymorphisms with Graves' disease and ophthalmopathy in Chinese children.  Invest Ophthalmol Vis Sci 2008;49:2409-15.

  61. Wong GW, Chow CM. Childhood asthma epidemiology: insights from comparative studies of rural and urban populations.  Pediatr Pulmonol 2008;43:107-16.

  62. Leung TF, Chan IH, Wong GW, Li CY, Tang NL, Yung E, Lam CW.  Association between candidate genes and lung function growth in Chinese asthmatic children. Clin Exp Allergy 2007;37:1480-6.

  63. Anderson HR, Gupta R, Kapetanakis V, Asher MI, Clayton T, Robertson CF, Strachan DP; Wong GW (ISAAC Steering Committee).  International correlations between indicators of prevalence, hospital admissions and mortality for asthma in children.  Int J Epidemiol. 2008;37:573-82.

  64. Ko FW, Tam W, Wong TW, Lai CK, Wong GW, Leung TF, Ng SS, Hui DS.  Effects of air pollution on asthma hospitalization rates in different age groups in Hong Kong. Clin Exp Allergy 2007;37:1312-9.

  65. Zimmet P, Alberti KG, Kaufman F, Tajima N, Silink M, Arslanian S, Wong GW, Bennett P, Shaw J, Caprio S; IDF Consensus Group.  The metabolic syndrome in children and adolescents - an IDF consensus report.  Pediatr Diabetes 2007;8:299-306.

  66. Kong AP, Wong GW, Choi KC, Ho CS, Chan MH, Lam CW, Tong PC, Ozaki R, So WY, Ma RC, Lau JT, Chan JC.  Reference values for serum levels of insulin-like growth factor (IGF-1) and IGF-binding protein 3 (IGFBP-3) and their ratio in Chinese adolescents.  Clin Biochem 2007;40:1093-9.

  67. Zimmet P, Alberti G, Kaufman F, Tajima N, Silink M, Arslanian S, Wong GW, Bennett P, Shaw J, Caprio S, International Diabetes Federation Task Force on Epidemiology and Prevention of Diabetes.  The metabolic syndrome in children and adolescents.  Lancet 2007;369:2059-61.

  68. Weinmayr G, Weiland SK, Björkstén B, Brunekreef B, Büchele G, Cookson WO, Garcia-Marcos L, Gotua M, Gratziou C, van Hage M, von Mutius E, Riikjärv MA, Rzehak P, Stein RT, Strachan DP, Tsanakas J, Wickens K, Wong GW.  Atopic sensitization and the international variation of asthma symptom prevalence in children.  Am J Respir Crit Care Med. 2007;176:565-74.

  69. Wong GW, Leung TF. Bird flu: lessons from SARS.  Paediatr Respir Rev. 2007;8(2):171-6.

  70. Chan IH, Tang NL, Leung TF, Ma SL, Zhang YP, Wong GW, Wong CK, Lam CW. Allergy Association of prostaglandin-endoperoxide synthase 2 gene polymorphisms with asthma and atopy in Chinese children 2007;62:802-9.

  71. Ng VW, Kong AP, Choi KC, Ozaki R, Wong GW, So WY, Tong PC, Sung RY, Xu LY, Chan MH, Ho CS, Lam CW, Chan JC.  BMI and waist circumference in predicting cardiovascular risk factor clustering in Chinese adolescents.  Obesity 2007;15:494-503.

  72. Wong GW, Leung TF, Ma Y, Liu EK, Yung E, Lai CK.  Symptoms of asthma and atopic disorders in preschool children: prevalence and risk factors.  Clin Exp Allergy 2007;37:174-9.

  73. Ozaki R, Qiao Q, Wong GW, Chan MH, So WY, Tong PC, Ho CS, Ko GT, Kong AP, Lam CW, Tuomilehto J, Chan JC.  Overweight, family history of diabetes and attending schools of lower academic grading are independent predictors for metabolic syndrome in Hong Kong Chinese adolescents.  Arch Dis Child 2007;92:224-8.

  74. Leung TF, Tang NL, Sung YM, Li CY, Ma SL, Lam CW, Wong GW.  Genetic association study between mbl2 and asthma phenotypes in Chinese children.  Pediatr Allergy Immunol. 2006;17:501-7.

  75. Wong GW.  Developing world: Asthma in a rural setting.  Paediatr Respir Rev. 2006;7 Suppl 1:S119-20.

  76. Wong GW.  Out of the East - Emerging infections.  Paediatr Respir Rev. 2006;7 Suppl 1:S229-31.  

  77. Lee V, Cheng PS, Chik KW, Wong GW, Shing MM, Li CK.  Autoimmune hypothyroidism after unrelated haematopoietic stem cell transplantation in children.  J Pediatr Hematol Oncol. 2006;28:293-5.

  78. Leung TF, Liu EK, Li CY, Chan IH, Yung E, Lam CW, Wong GW.  Lack of association between NOS2 pentanucleotide repeat polymorphism and asthma phenotypes or exhaled nitric oxide concentration.  Pediatr Pulmonol. 2006;41:649-55.

  79. Wong GW, von Mutius E, Douwes J, Pearce N.  Environmental determinants associated with the development of asthma in childhood.  Int J Tuberc Lung Dis. 2006;10:242-51.

  80. Wang HY, Chen YZ, Ma Y, Wong GW, Lai CK, Zhong NS.  Disparity of asthma prevalence in Chinese schoolchildren is due to differences in lifestyle factors Zhonghua Er Ke Za Zhi 2006;44:41-5.

  81. Leung TF, Li CY, Liu EK, Tang NL, Chan IH, Yung E, Wong GW, Lam CW.  Asthma and atopy are associated with DEFB1 polymorphisms in Chinese children. Genes Immun 2006;7:5964.

  82. Chan IHC, Leung TF, Tang NL , Li CY, Sung YM, Wong GW, Wong CK and Lam CW.  Gene-gene interactions for asthma and plasma total IgE concentration in Chinese children.  J Allergy Clin Immunol. 2006;117:127-33.

  83. Hui LL, Nelson EA, Choi KC, Wong GW, Sung R.  Twelve-Hour Glycemic Profiles With Meals of High, Medium, or Low Glycemic Load.  Diabetes Care 2005 ;28(12):2981-3.

  84. Leung TF, Li CY, Yung E, Liu EK, Lam CW, Wong GW.  Clinical and Technical Factors Affecting pH and Other Biomarkers in Exhaled Breath Condensate. Pediatr Pulmonol. 2006;41(1):87-94.

  85. Leung TF, Liu EK, Tang NL, Ko FW, Li CY, Lam CW, Wong GW.  Nitric oxide synthase polymorphisms and asthma phenotypes in Chinese children.  Clin Exp Allergy. 2005;35:1288-94.

  86. FWS Ko, CYK Lau, TF Leung, GW Wong, CWK Lam, CKW Lai, DSC Hui. Exhaled breath condensate levels of eotaxin and macrophage-derived chemokine in stable adult asthma patients.  Clin Exp Allergy 2006;36:44-51.

  87. Ko FW, Wang HY, Wong GW, Leung TF, Hui DS, Chan DP, Zhong NS, Lai CK. Wheezing in Chinese schoolchildren: disease severity distribution and management practices, a community-based study in Hong Kong and Guangzhou.  Clin Exp Allergy 2005;35:1449-56.   

  88. Ko FW, Lau CY, Leung TF, Wong GW, Lam CW, Hui DS.  Exhaled breath condensate levels of 8-isoprostane, growth related oncogene alpha and monocyte chemoattractant protein-1 in patients with chronic obstructive pulmonary disease. Respir Med 2006;100:630-8.

  89. Leung TF, Wong GW, Ko FW, Lam CW, Fok TF.  Clinical and atopic parameters and airway inflammatory markers in childhood asthma: a factor analysis.  Thorax 2005;60:822-6.

  90. Yeung WL, Lam CW, Cheng WT, Sin NC, Wong GW, Wong CN, Tse KM, Fok TF. Early-onset primary torsional dystonia in a 4-generation Chinese family with a mutation in the DYT1 gene.  Chin Med J. 2005;118(10):873-6.

  91. Ma Y, Liu CH, Wong GW.  Exhaled nitric oxide in asthma.  Zhonghua Er Ke Za Zhi 2005 Jun;43(6):421-2.

  92. Wong GW, Liu EKH, Leung TF, Yung E, Ko FWS, Hui DSC, Fok TF, Lai CKW. High levels and gender difference of exhaled nitric oxide in Chinese schoolchildren. Clinical & Experimental Allergy 2005;35:889-93. 

  93. Leung TF, Tang NL, Wong GW, Fok TF.  CD14 and Toll-Like Receptors: Potential Contribution of Genetic Factors and Mechanisms to Inflammation and Allergy.  Curr Drug Targets Inflamm Allergy 2005;4:169-75.

  94. Leung TF, Wong GW, Ko FW, Li CY, Yung E, Lam CW, Fok TF.  Analysis of Growth Factors and Inflammatory Cytokines in Exhaled Breath condensate from asthmatic children.  Int Arch Allergy Immunol. 2005;137:66-72.

  95. Leung TF, Tang NLS, Lam CWK, Li AM, Fung SLM, Chan HIS, Wong GW. RANTES G-401A polymorphism is associated with allergen sensitization and FEV1 in Chinese children.  Respiratory Medicine 2005;99:216-9.

  96. Zhong NS, Wong GW.  Epidemiology of Severe Acute Respiratory Syndrome (SARS): adults and children.  Paediatr Respir Rev 2004 Dec;5(4):270-4.

  97. Hui DSC, Wong GW.  Advancements in the battle against Severe Acute Respiratory Syndrome (SARS).  Expert Opinion in Pharmacotherapy 2004;5:1687-93.

  98. Wong GW, Leung TF, Ko FWS, Lee KKM, Lam P, Hui DSC, Fok TF, Lai CK. Declining asthma prevalence in Hong Kong Chinese schoolchildren.  Clin Exp Allergy 2004 Oct;34(10):1550-5.

  99. Leung TF, Tang NL, Li CY, Lam CWK, Wong GW, Fok TF.  Association between TARC C-431T and atopy and asthma in children. J Allergy Clin Immunol. 2004;114:199-202.

  100. Wong GW, Ko FW, Hui DS, Fok TF, David Carr, Erika von Mutius, Zhong NS, Chen YZ, Lai CKW.  Disparity of asthma prevalence and lifestyle factors: A multi-centre epidemiological survey of children from three Chinese cities.  British Medical Journal 2004;329(7464):486.

  101. Li CK, Chik KW, Wong GW, Cheng PS, Shing MMK, Lee V, Yuen PMP.  Growth and endocrine function following bone marrow transplantation for thalassemia major. Pediatr Hematol Oncol 2004;21(5):411-9.

  102. Leung TF, Li CY, Lam CWK, Au CSS, Yung E, Chan HIS, Wong GW, Fok TF.  The relation between obesity and asthmatic airway inflammation.  Pediatr Allergy Immunology 2004;15:344-50.

  103. Wong GW, Leung TF, Fok TF.  Asthma epidemiology and hygiene hypothesis in Asia.  Allergy Clin Immunol Int-J World Allergy Org 2004;16:155-60.

  104. Leung TF, Wong GW, Ko FW, Lam CW, Fok TF.  Increased macrophage-derived chemokine in exhaled breath condensate and plasma from children with asthma.  Clin Exp Allergy 2004;34:786-91.

  105. Sandford AJ, Chan HW, Wong GW, Lai CK, Chan-Yeung M.  Candidate genetic polymorphisms for asthma in Chinese schoolchildren from Hong Kong.  Int J Tuberc Lung Dis. 2004 May;8(5):519-27.

  106. Leung TF, Ng PC, Cheng FW, Lyon DJ, So KW, Hon EK, Li AM, Li CK, Wong GW, Nelson EA, Hui J, Sung RY, Yam MC, Fok TF.  Infection control for SARS in a tertiary paediatric centre in Hong Kong.  J Hosp Infect. 2004 Mar;56(3):215-22.

  107. Wong GW, Leung TF, Fok TF.  ISAAC and risk factors for asthma in the Asia-Pacific.  Paediatr Respir Rev. 2004;5 Suppl A:S163-9.

  108. Wong GW, Leung TF, Fok TF.  Outdoor air pollution and asthma.  Pediatr Pulmonol. 2004;37 S26:220-2.

  109. Wong GW, Fok TF.  Severe acute respiratory syndrome (SARS) in children. Pediatr Pulmonol. 2004;37(S26):69-71.

  110. Wong GW, Lai CK.  Outdoor air pollution and asthma.  Curr Opin Pulm Med. 2004;10:62-6.

  111. Chen YZ, Ma Y, Wang HY, Wang HJ, Zhao J, Cao L, Li S, Wong GW, Zhong NS, Fok TF, Lai CK. Allergens as risk factors for asthma and bronchial hyperresponsiveness in Chinese children. Chinese Journal of Pediatrics. 2003;41:538-41.

  112. Ma Y, Li XF, Zhao J, Wong GW, Zhou CS, Chen YZ.  Relationships between the diameters of Bacille Calmette-Guerin scars and asthma, atopy in urban and rural Beijing children.  Chin J Turberc Respir Dis 2003;26:526-30.

  113. Leung TF, Wong GW, Hon KL, Fok TF.  Severe acute respiratory syndrome (SARS) in children: epidemiology, presentation and management. Paediatr Respir Rev. 2003 Dec;4(4):334-9. 

  114. Wong GW, Li AM, Ng PC, Fok TF. Severe acute respiratory syndrome in children. Pediatr Pulmonol. 2003;36:261-6. 

  115. Leung TF, Tam WH, Hung EC, Fok TF, Wong GW.  Sociodemographic and atopic factors affecting breastfeeding intention in Chinese mothers.  J Paediatr Child Health 2003;39:460-4. 

  116. Leung TF, Tang NL, Sung YM, Li AM, Wong GW, Chan IH, Lam CW.  The C-159T polymorphism in the CD14 promoter is associated with serum total IgE concentration in atopic Chinese children.  Pediatr Allergy Immunol. 2003;14:255-60.

  117. Wong GW, Hui DS.  Severe acute respiratory syndrome (SARS): epidemiology, diagnosis and management.  Thorax 2003;58:558-60.

  118. Chan YL, Chu WC, Wong GW, Yeung DK.  Diffusion-weighted MRI in shaken baby syndrome.  Pediatr Radiol. 2003;33:574-7.

  119. Leung TF, Wong CK, Lam CW, Li AM, Ip WK, Wong GW, Fok TF.  Plasma TARC concentration may be a useful marker for asthmatic exacerbation in children.  Eur Respir J. 2003;21:616-20.

  120. Leung TF, Wong CK, Chan IH, Ip WK, Lam CW, Wong GW.  Plasma concentration of thymus and activation-regulated chemokine is elevated in childhood asthma.   J Allergy Clin Immunol. 2002;110:404-9.

  121. Yung E, Cheng PS, Fok TF, Wong GW.  CTLA-4 gene A-G polymorphism and childhood Graves' disease.  Clin Endocrinol  2002;56:649-53.

  122. Chan WM, Wong GW, Ng JS, Fan DS, Cheng AC, Lam DS.  Ophthamopathy in childhood Graves’ disease.  British Journal of Ophthalmology 2002;86:740-2.

  123. Wong GW, Li ST, Hui DS, Fok TF, Zhong NS, Chen YZ, Lai CK.  Individual allergens as risk factors for asthma and bronchial hyperresponsiveness in Chinese children.  European Respiratory Journal 2002;19:288-93.

  124. Chan LY, Lau TK, Chiu PY, Wong GW, Leung TN.  Cord blood thyroid stimulating hormone level after external cephalic version.  British Journal of Obstetrics and Gynaecology 2001;108:1076-80.

  125. Ng PC, Lam CW, Wong GW, Lee CH, Cheng PS, Fok TF, Chan IH, Wong E, Cheung K, Lee SY.  Changes in markers of bone metabolism during dexamethasone treatment for chronic lung disease in preterm infants.  Archives of Diseases in Childhood 2001 2002;86(1):F49-54.

  126. Wong GW, Hui DS, Tam CM, Chan HH, Fok TF, Chan-Yeung M, Lai CW.  Asthma, atopy and tuberculin responses in Chinese schoolchildren in Hong Kong.  Thorax 2001;56:770-3.

  127. Wong GW, Hui, DS, Chan HH, Fok TF, Leung R, Zhong NS, Chen YZ, Lai CK. Prevalence of respiratory and atopic disorders in Chinese schoolchildren.  Clinical and Experimental Allergy 2001;31:1225-31.

  128. Chan HH, Pei A, Van Krevel C, Wong GW, Lai CK.  Validation of the Chinese translated version of ISAAC core questions for atopic eczema.  Clinical and Experimental Allergy 2001;31:903-7. 

  129. Wong GW, Cheng PS.  Increasing incidence of childhood Graves’ disease in Hong Kong: A follow-up study.  Clinical Endocrinology 2001;54:547-50.

  130. Wong GW, Ko FW, Lau TS, Li ST, Hui D, Pang  SW, Leung R, Fok TF, Lai CK. Temporal relationship between air pollution and hospital admissions for asthmatic children in Hong Kong.  Clinical and Experimental Allergy 2001;31:565-9.


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